ADVI Health partners with pharmaceutical and biotech organizations to advance their evidence generation and market access strategies. We support complex research questions through primary research (e.g., surveys and chart reviews), secondary dataset analyses using our CMS Virtual Research Data Center (VRDC) innovator license, and RAND/UCLA Modified Delphi expert panels.

Our team combines expertise in data science, clinical research, innovation, and payer strategy. 

Specifically, our RAND/UCLA Modified Delphi panel work helps clients: 

  • Assess clinical practice patterns and treatment pathways 
  • Generate expert consensus where published evidence is limited 
  • Support HEOR and market access initiatives 
  • Inform evidence generation and commercialization strategy 
  • Develop payer- and stakeholder-focused insights 

What is a RAND/UCLA Modified Delphi Panel?

A validated approach for developing clinical appropriateness criteria and achieving consensus on complex clinical decisions when evidence is limited or conflicting.

  • Unlike other Delphi approaches, it combines scientific evidence review with expert clinical judgment, including a virtual or in-person panel meeting, to generate robust consensus.
  • The RAND/UCLA modified Delphi method is a structured consensus process that combines expert opinion and evidence through iterative rating and discussion to develop clear, credible guidance.

Executing this methodology involves a structured, four-phase journey. Phase I lays the essential groundwork with a formal study kick-off, a targeted literature summary, and the initial recruitment and contracting of expert panelists. In Phase II, the focus shifts to collaboration as we work directly with the panel to develop tailored rating forms, which the experts then use to complete their initial pre-meeting ratings. Phase III drives the core consensus through a dynamic panel meeting, held either virtually or in person, where experts discuss the data and variations, followed by the completion of final post-meeting ratings. Finally, Phase IV synthesizes the results, working alongside panelists to develop formal consensus statements and translating the final insights into a comprehensive study report, publishable abstracts, and manuscripts.

Get in touch to learn more about how we can help support and enhance your evidence generation and commercialization strategies.

See our most recent publications here.


Caitlin Sheetz, MPH
Senior Vice President and Head of Strategic Analytics, Value and Economics

CEO insights

Real analysis from people who’ve been there

Cell and Gene Precision Medicine State Policy

The 2026 Rare Disease Reality

Orphan drugs now represent approximately 20 percent of total prescription spend, and over 52 percent of the cell and gene …

Marc Samuels, JD, MPH
February 26, 2026

Uncategorized

How HEOR and Real-World Evidence Are Reshaping Decisions in 2026

By 2026, health economics and outcomes research (HEOR) and real-world evidence (RWE) will look less like a supporting function and …

February 10, 2026

Precision Medicine

2026 Life Sciences Forecast: AI, Next-Gen Cell & Gene Therapy, and Policy Disruption

In 2026, we expect the healthcare landscape to be defined by technology breakthroughs, market access disruption, and profound policy changes. …

Marc Samuels, JD, MPH
December 16, 2025

Inflation Reduction Act

Real-World Effectiveness vs Clinical Trial Efficacy in Medicare

The Inflation Reduction Act (IRA) has ushered in a new era of drug pricing negotiations in the US. For the …

October 1, 2025

Inflation Reduction Act Pharmaceuticals and Biotech

Why is Medicare Data Central to IRA Negotiations?

The Inflation Reduction Act (IRA), passed in 2022, has transformed the way drug pricing will be managed in the United …

September 10, 2025

Pharmaceuticals and Biotech

PHAR Partners Present at the National Bleeding Disorders Conference

Jonathan James, patient and patient advocate for a hemophilia advocacy group, partnered with PHAR (Partnership for Health Analytic Research) and …

September 16, 2024

ADVI Research: Impact of the COVID-19 Pandemic on Healthcare Utilization Among Medicare Beneficiaries with CVD

ADVI Health Strategic Analytics, Value and Economics (SAVEs) data analyst, David Liu, and the team presented four poster presentations at …

May 25, 2024

ADVI Angle Vertical

Cell and Gene

ADVI Research: Medicare Beneficiaries with Multiple Administrations of CAR-T

ADVI Health Strategic Analytics, Value and Economics (SAVEs) chief data scientist, Pete Kardel, and the team presented four poster presentations …

Peter Kardel, MA
May 21, 2024

Reach out

Own your edge

We don’t just guide the market. We shape it. Map your market access moves with #ADVIIntelligence. Proven advantage. Unmatched partnership.